
NCEF: FILORGA’S SIGNATURE INGREDIENT
<p><b>Published November 28, 2022</b></p>
<p><span style="font-weight: 400;">Laboratoires FILORGA’s story begins in 1978, when Dr. Michel Tordjman invented a unique injectable anti-aging solution capable of acting on the processes that influence skin aging. This was followed by close collaboration with aesthetic doctors from all over the world who adopted FILORGA products — particularly Dr. Tordjman’s poly-revitalizing solution.</span></p>
<p><span style="font-weight: 400;">But, regardless of their effectiveness, injections can be intimidating to some people. So, with the objective of making their scientific and aesthetic expertise as widely available as possible, FILORGA’s experts developed NCEF [New Cellular Encapsulated Factors], a unique complex directly inspired by the anti-aging solution invented by Dr. Tordjman over 45 years ago.</span></p>
<p><span style="font-weight: 400;">It is this signature Laboratoires FILORGA ingredient that we are going to look at today.</span></p>
<h2><b>HOW DOES NCEF WORK? </b></h2>
<p><b><img alt="NCEF, FILORGA’s game changer, is a unique complex that forms the backbone of our anti-aging treatments" src="https://cdn.shopify.com/s/files/1/0557/0369/9549/files/SEARCH-PIPETTE-1x1_240x240.jpg?v=1691166508"></b></p>
<p><span style="font-weight: 400;">NCEF is the core complex of Laboratoires FILORGA's unique formula. It provides elements that are essential for the proper functioning of the cells while respecting the skin's natural mechanisms. </span></p>
<p><span style="font-weight: 400;">In order to cross the skin barrier and distribute the active ingredients throughout the skin’s various </span><a href="https://us.filorga.com/articles/understand-the-structure-of-your-skin-to-take-care-of-it"><b>layers</b></a><span style="font-weight: 400;">, FILORGA employs state-of-the-art encapsulation technology resulting from scientific research: the ingredients are </span><b>encapsulated</b><span style="font-weight: 400;"> in multilamellar liposomes — small spheres made up of around a hundred microscopic layers between which the active ingredients are inserted. The outer layers are made up of phospholipids, which are able to </span><b>cross the skin barrier</b><span style="font-weight: 400;"> thanks to their molecules’ affinity with epidermal cells.</span></p>
<p><span style="font-weight: 400;">The liposomes act as small vehicles for the active ingredients which, upon arriving at their destination, are released into the deeper layers of the skin to begin their task of </span><b>repairing, moisturizing,</b><span style="font-weight: 400;"> or </span><b>nourishing</b><span style="font-weight: 400;">.</span></p>
<h2><b>WHAT ARE NCEF’S ACTIVE INGREDIENTS?</b></h2>
<p><b><img src="https://cdn.shopify.com/s/files/1/0557/0369/9549/files/SEARCH-ROSE-1x1_240x240.jpg?v=1691166403" alt="NCEF includes active ingredients used in cosmetic injections"></b></p>
<p><span style="font-weight: 400;">NCEF incorporates a complex of ingredients, </span><b>the same as those used in injections:</b></p>
<p><span style="font-weight: 400;">- High molecular weight </span><a href="https://us.filorga.com/the-benefits-of-hyaluronic-acid"><b>hyaluronic acid</b></a></p>
<p>- Amino acids</p>
<p>- Vitamins</p>
<p>- Minerals</p>
<p>- Coenzymes</p>
<p><span style="font-weight: 400;">If you would like to learn more about the active ingredients in NCEF and how they work to fill in wrinkles and revitalize the skin, our experts have written </span><a href="https://us.filorga.com/articles/ncef-the-secrets-of-filorga-s-signature-complex"><b>this article about the secrets of our signature complex</b></a><span style="font-weight: 400;">. </span></p>
<p><span style="font-weight: 400;">Once its active ingredients are released, NCEF acts as a veritable </span><b>booster</b><span style="font-weight: 400;">, activating the skin's natural cellular mechanisms to fight signs of skin aging. To establish its effectiveness, FILORGA conducted ex vivo tests on human skin explants. The results demonstrated, among other things, that the activity of fibroblasts (the cells of the dermis that produce collagen, elastin, and hyaluronic acid) was stimulated.</span></p>
<p><span style="font-weight: 400;">This resulted in: </span></p>
<p>- A significant 70% increase in the amount of <a href="https://us.filorga.com/articles/the-role-of-collagen-and-elastin-in-healthy-skin"><b>collagen</b></a>*</p>
<p>- A significant 22% increase in the amount of <b>elastin</b>*</p>
<p><span style="font-weight: 400;">NCEF is the key compound in all of Laboratoires FILORGA's skin care products.** </span></p>
<h2>
<b>SPOTLIGHT ON NCEF-SHOT — FILORGA's most concentrated NCEF product</b><span style="font-weight: 400;">!</span>
</h2>
<div style="text-align: left;"><img src="https://cdn.shopify.com/s/files/1/0557/0369/9549/products/NCEFShotSmear_240x240.png?v=1683129464" alt="Filorga's NCEF-Shot 10 day anti-aging treatment" style="float: none;"></div>
<p><a href="https://us.filorga.com/products/ncef-shot"><b>NCEF-SHOT</b></a><span style="font-weight: 400;"> is an innovative anti-aging product in the </span><a href="https://us.filorga.com/collections/ncef"><b>NCEF skin care collection</b></a><span style="font-weight: 400;">. It is designed to be used as a 10-day treatment when your skin needs some extra help to deal with </span><b>seasonal changes</b><span style="font-weight: 400;"> or to cope with </span><b>stress</b><span style="font-weight: 400;"> and </span><b>fatigue</b><span style="font-weight: 400;">. </span></p>
<p><span style="font-weight: 400;">Each application of NCEF-SHOT works on </span><b>wrinkles</b><span style="font-weight: 400;"> and bolsters </span><b>firmness</b><span style="font-weight: 400;"> and </span><b>radiance</b><span style="font-weight: 400;">, providing a complete and fast-acting anti-aging solution. It complements your daily beauty routine and should be applied morning and night before your serum and cream.</span></p>
<p><span style="font-weight: 400;">Easy-to-use and easy-to-dose thanks to its 0.75 ml graduated pipette, NCEF-SHOT received praise in all </span><a href="https://us.filorga.com/articles/cosmetic-tests-filorga-conducts-on-its-products"><b>self-evaluation questionnaires</b></a><span style="font-weight: 400;">: 9 out of 10 women noted a significant improvement in the quality of their skin*** after 10 days of twice-daily application of NCEF-SHOT. </span></p>
<p><span style="font-weight: 400;">Explore the other products in the </span><a href="https://us.filorga.com/collections/ncef"><b>NCEF</b></a><b> </b>a<span style="font-weight: 400;">nti-aging product family, which is the FILORGA collection enriched with the most NCEF. </span></p>
<p> </p>
<p><span style="font-weight: 400;">*Ex vivo tests — Measurement of the amount of collagen and elastin after application of NCEF on skin explants for 5 days versus control.</span></p>
<p><span style="font-weight: 400;">**Except our sheet masks, micellar solution, and foam cleanser.</span></p>
<p><span style="font-weight: 400;">***Self-evaluation — 30 subjects after 10 days of twice-daily application of NCEF-SHOT Concentrate.</span></p>